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Symbol Name ID |
Aurka
aurora kinase A MGI:894678 |
| Darker colors indicate more annotations |
| Human Phenotypes | Dysgerminoma |
Ovarian papillary adenocarcinoma |
Uterine leiomyosarcoma |
| Disease(s) Associated with AURKA | |||
| colorectal cancer | |||
| ovarian cancer |
| Mouse Phenotypes | abnormal sperm midpiece morphology |
kinked sperm flagellum |
multiflagellated sperm |
azoospermia |
oligozoospermia |
teratozoospermia |
abnormal sperm head morphology |
absent germ cells |
abnormal female meiosis I arrest |
abnormal meiotic spindle morphology |
increased male germ cell apoptosis |
abnormal sperm motility |
increased sperm progressive motility |
decreased corpora lutea number |
abnormal seminiferous tubule morphology |
abnormal seminiferous tubule epithelium morphology |
decreased testis weight |
small testis |
abnormal cauda epididymis morphology |
female infertility |
decreased litter size |
reduced male fertility |
abnormal sperm physiology |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Aurkatm1.1Tvd/Aurkatm1.1Tvd Tg(Ddx4-cre)1Dcas/0 (conditional) |
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| Aurkatm1.1Tvd/Aurkatm1.1Tvd Ccn6tm1(cre)Mawa/Ccn6+ (conditional) |
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| Aurkatm1c(EUCOMM)Hmgu/Aurkatm1c(EUCOMM)Hmgu Tg(Gdf9-icre)5092Coo/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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